BETA-(AMINOMETHYL)-4-CHLOROBENZENEETHANESULFONIC ACID
SACLOFEN
CAS: 125464-42-8
Molecular Formula: C9H12ClNO3S
BETA-(AMINOMETHYL)-4-CHLOROBENZENEETHANESULFONIC ACID - Names and Identifiers
| Name | SACLOFEN |
| Synonyms | SACLOFEN SACLOFEN SELECTIVE GABA(B) REC 3-AMINO-2-(4-CHLOROPHENYL)-PROPANE SULFONIC ACID 3-AMino-2-(4-chlorophenyl)propane-1-sulfonic acid (RS)-3-amino-2-(4-chlorophenyl)propylsulfonic acid β-(aminomethyl)-4-chlorobenzeneethanesulfonic acid (RS)-3-AMINO-2-(4-CHLOROPHENYL)PROPYLSULFONIC ACID BETA-(AMINOMETHYL)-4-CHLOROBENZENEETHANESULFONIC ACID BETA-(AMINOMETHYL)-4-CHLORO-BENZENEETHANESULPHONIC ACID |
| CAS | 125464-42-8 |
| InChI | InChI=1/C9H12ClNO3S/c10-9-3-1-7(2-4-9)8(5-11)6-15(12,13)14/h1-4,8H,5-6,11H2,(H,12,13,14) |
| InChIKey | JYLNVJYYQQXNEK-UHFFFAOYSA-N |
BETA-(AMINOMETHYL)-4-CHLOROBENZENEETHANESULFONIC ACID - Physico-chemical Properties
| Molecular Formula | C9H12ClNO3S |
| Molar Mass | 249.71 |
| Density | 1.437±0.06 g/cm3(Predicted) |
| Melting Point | 310-315℃ (decomposition) |
| Solubility | 0.1 M NaOH: 20mg/mL |
| Appearance | solid |
| Color | white |
| pKa | 1.15±0.50(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.6 |
| Physical and Chemical Properties | Solubility: 0.1 M NaOH: 20 mg/mL WGK Germany:3 |
BETA-(AMINOMETHYL)-4-CHLOROBENZENEETHANESULFONIC ACID - Risk and Safety
| WGK Germany | 3 |
BETA-(AMINOMETHYL)-4-CHLOROBENZENEETHANESULFONIC ACID - Introduction
3-Amino -2-(4-chlorophenyl)-propanesulfonic acid (abbreviated as ACPA) is an organic compound. It has a chemical formula of C9H12ClNO3S and a molecular weight of about 239.71g/mol.
ACPA is a solid, usually white crystalline powder. It is stable at room temperature, but may decompose at high temperatures or under the action of strong acids. ACPA has a high solubility in water and a relatively low solubility in organic solvents.
ACPA has pharmaceutical activity and is widely used as a pharmaceutical intermediate. It is a non-guanine PPARγ agonist and is used in the field of diabetes treatment. In addition, ACPA can also be used to synthesize other drugs, such as anti-tumor drugs and anti-inflammatory drugs.
The preparation of ACPA is usually achieved by chemical synthesis. A common synthetic method is to react 4-chloroacetophenone with sulfuric acid and an oxidizing agent to produce 3-amino -2-(4-chlorophenyl)-propenone, which is then reacted with threesulfonic acid to form ACPA.
Some safety information needs to be paid attention to when using and handling ACPA. It is irritating and may cause irritation to the eyes, skin and respiratory tract. Therefore, it is necessary to wear appropriate personal protective equipment, such as safety glasses, gloves and respiratory protection equipment. At the same time, it should be used in a well-ventilated laboratory environment and avoid contact with strong acids and strong oxidants to avoid dangerous reactions.
In summary, 3-amino -2-(4-chlorophenyl)-propanesulfonic acid is an organic compound with pharmaceutical activity and has important applications in the fields of drug synthesis and diabetes treatment. However, safety precautions should be paid attention to when using and handling.
ACPA is a solid, usually white crystalline powder. It is stable at room temperature, but may decompose at high temperatures or under the action of strong acids. ACPA has a high solubility in water and a relatively low solubility in organic solvents.
ACPA has pharmaceutical activity and is widely used as a pharmaceutical intermediate. It is a non-guanine PPARγ agonist and is used in the field of diabetes treatment. In addition, ACPA can also be used to synthesize other drugs, such as anti-tumor drugs and anti-inflammatory drugs.
The preparation of ACPA is usually achieved by chemical synthesis. A common synthetic method is to react 4-chloroacetophenone with sulfuric acid and an oxidizing agent to produce 3-amino -2-(4-chlorophenyl)-propenone, which is then reacted with threesulfonic acid to form ACPA.
Some safety information needs to be paid attention to when using and handling ACPA. It is irritating and may cause irritation to the eyes, skin and respiratory tract. Therefore, it is necessary to wear appropriate personal protective equipment, such as safety glasses, gloves and respiratory protection equipment. At the same time, it should be used in a well-ventilated laboratory environment and avoid contact with strong acids and strong oxidants to avoid dangerous reactions.
In summary, 3-amino -2-(4-chlorophenyl)-propanesulfonic acid is an organic compound with pharmaceutical activity and has important applications in the fields of drug synthesis and diabetes treatment. However, safety precautions should be paid attention to when using and handling.
Last Update：2024-04-09 21:11:58
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View History
BETA-(AMINOMETHYL)-4-CHLOROBENZENEETHANESULFONIC ACID
洛索洛芬EP杂质K
4-甲基-6,7-二氢-5H-环戊二烯[B]吡啶-2-醇
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吉拉尔特试剂
N-4-Boc-2-哌嗪甲酸
3-HYDROXY-PROPIONAMIDINE
洛索洛芬EP杂质K
4-甲基-6,7-二氢-5H-环戊二烯[B]吡啶-2-醇
2-(2-(1-萘甲酰基)-8-氟-1.2.3.4-四氢吡啶并[4,3-B]吲哚-5基)乙酸
Cyclohexanamine, N-[(1-piperidinylthioxomethyl)thio]-
高纯碳酸钡
CyclopentaneMethanol, 1-aMino-
吉拉尔特试剂
N-4-Boc-2-哌嗪甲酸
3-HYDROXY-PROPIONAMIDINE